{"id":3179,"date":"2021-07-09T11:49:05","date_gmt":"2021-07-09T11:49:05","guid":{"rendered":"https:\/\/www.molecular-view.com\/?page_id=3179"},"modified":"2021-08-25T11:50:44","modified_gmt":"2021-08-25T11:50:44","slug":"gene_expression_of_antiapoptotic_genes","status":"publish","type":"page","link":"https:\/\/www.molecular-view.com\/el\/services\/cancer\/prognosis_diagnosis\/gene_expression_of_antiapoptotic_genes\/","title":{"rendered":"\u0393\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ae \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 (\u03c0\u03bf\u03c3\u03bf\u03c4\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7) \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b1\u03c0\u03bf\u03c0\u03c4\u03c9\u03c4\u03b9\u03ba\u03ce\u03bd \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd"},"content":{"rendered":"<div id=\"pl-3179\"  class=\"panel-layout\" ><div id=\"pg-3179-0\"  class=\"panel-grid panel-has-style\" ><div class=\"divider-no-animation panel-row-style panel-row-style-for-3179-0\" ><div id=\"pgc-3179-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-3179-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\" ><div class=\"orion custom default panel-widget-style panel-widget-style-for-3179-0-0-0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t><h3 class=\"widget-title\">\u0393\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ae \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 (\u03c0\u03bf\u03c3\u03bf\u03c4\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7) \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b1\u03c0\u03bf\u03c0\u03c4\u03c9\u03c4\u03b9\u03ba\u03ce\u03bd \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd<\/h3>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>&nbsp;<\/p>\n<ul>\n<li>BCL2<\/li>\n<\/ul>\n<p>Bcl-2 ( B-cell lymphoma 2 ) \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03b9\u03b4\u03c1\u03c5\u03c4\u03b9\u03ba\u03cc \u03bc\u03ad\u03bb\u03bf\u03c2 \u03c4\u03b7\u03c2\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Apoptosis_regulator_proteins,_Bcl-2_family&amp;usg=ALkJrhit0O-QNA8CRWpSH6wQJj0cukBfVA\">Bcl-2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2<\/a>\u00a0\u03c4\u03b7\u03c2\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/searchqBCL2wikipediahlelbiw1440bih619prmdimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Regulator_protein&amp;usg=ALkJrhgiOmIzV9PQtumNLUktYMPNnd_5Og\">\u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7<\/a>\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/searchqBCL2wikipediahlelbiw1440bih619prmdimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Apoptosis&amp;usg=ALkJrhjvORb5jEluhXn8IX0PzpYPT9uQdw\">\u03ba\u03b1\u03b9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03c4\u03ce\u03bd \u03c4\u03b7\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03b7\u03c2<\/a>\u00a0BCL2\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Gene&amp;usg=ALkJrhgCCF-yQRVwC174lCROoE3dFtQxnQ\">\u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf<\/a>\u0388\u03c7\u03b5\u03b9 \u03b5\u03bc\u03c0\u03bb\u03b1\u03ba\u03b5\u03af \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03c3\u03b5\u03b9\u03c1\u03ac\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Cancer&amp;usg=ALkJrhjv6JBbGETGwAM_43zscC7cVEYKYA\">\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03c9\u03bd<\/a>\u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03bf\u03c5\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Melanoma&amp;usg=ALkJrhi3-O2bDjeFd7fgn66qoArWk5cViw\">\u03c4\u03bf\u03c5 \u03bc\u03b5\u03bb\u03b1\u03bd\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2<\/a>,\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Breast_cancer&amp;usg=ALkJrhi1YDEPe196vvvBrfoXHOYvUxgQow\">\u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd<\/a>,\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Prostate_cancer&amp;usg=ALkJrhjqYTVPEa4GZz1JoV04boI2lDdn4A\">\u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c4\u03ac\u03c4\u03b7<\/a>,\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Chronic_lymphocytic_leukemia&amp;usg=ALkJrhgdg3C-gij-hWsHTbXqRvwEzS9W3Q\">\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03bb\u03b5\u03bc\u03c6\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03c5\u03c7\u03b1\u03b9\u03bc\u03af\u03b1<\/a>\u03ba\u03b1\u03b9\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Lung_cancer&amp;usg=ALkJrhiOzFn81XcQmy5wdD3kGu7Hd0SU8A\">\u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1<\/a>\u03ba\u03b1\u03b8\u03ce\u03c2 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Schizophrenia&amp;usg=ALkJrhgLoC7Q_rVl1I6ZHfVQwaq8eXCOJg\">\u03c3\u03c7\u03b9\u03b6\u03bf\u03c6\u03c1\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2<\/a>\u00a0\u03ba\u03b1\u03b9\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Autoimmunity&amp;usg=ALkJrhiNb0BMBbqKpsMzB2T5F5NakLPUiA\">\u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03c9\u03bd \u03bd\u03bf\u03c3\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd<\/a>\u0398\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03cc\u03c4\u03b9 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b8\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03b5 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5. \u0391\u03c5\u03c4\u03cc \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b1\u03af\u03b6\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5.\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Bcl-2_inhibitor&amp;usg=ALkJrhiZ8wOF-yMug7EcFAcyaFAeI9GYKA\">\u03a3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03bc\u03b5 \u03c4\u03b7 \u03b2\u03bf\u03ae\u03b8\u03b5\u03b9\u03b1 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03c9\u03bd \u03c4\u03bf\u03c5 BCL2<\/a>\u00a0\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd:\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Oligonucleotide&amp;usg=ALkJrhgMgojTyWQPZR72dJXAWNbZIjnuvg\">(\u03ad\u03bd\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03bf\u03bb\u03b9\u03b3\u03bf\u03bd\u03bf\u03c5\u03ba\u03bb\u03b5\u03bf\u03c4\u03b9\u03b4\u03af\u03c9\u03bd)<\/a>\u00a0drug\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Genasense&amp;usg=ALkJrhiqbHJDO-9Ecx45EvethheATVvZLg\">Genasense<\/a>,  \u0391\u0392\u03a4-737 (\u03ad\u03bd\u03b1 \u03bc\u03b9\u03ba\u03c1\u03cc \u03bc\u03cc\u03c1\u03b9\u03bf \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03b1) \u03c0\u03bf\u03bb\u03cd\u03c4\u03b9\u03bc\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03bb\u03b5\u03bc\u03c6\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03c9\u03bd \u03bc\u03bf\u03c1\u03c6\u03ce\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2, \u0391\u0392\u03a4-199 \u03b3\u03b9\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Chronic_lymphocytic_leukemia&amp;usg=ALkJrhgdg3C-gij-hWsHTbXqRvwEzS9W3Q\">\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03bb\u03b5\u03bc\u03c6\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03c5\u03c7\u03b1\u03b9\u03bc\u03af\u03b1<\/a>\u00a0\u03ba\u03b1\u03b9 Obatoclax (GX15-070) \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03ad\u03b4\u03c9\u03c3\u03b5 \u03b5\u03bd\u03b8\u03b1\u03c1\u03c1\u03c5\u03bd\u03c4\u03b9\u03ba\u03ac \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ad\u03c2 \u03c6\u03ac\u03c3\u03b7\u03c2 \u0399\u0399, \u03b3\u03b9\u03b1 \u03c4\u03bf\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3DBCL2%2Bwikipedia%26hl%3Del%26biw%3D1440%26bih%3D619%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;twu=1&amp;u=http:\/\/en.wikipedia.org\/wiki\/Small-cell_lung_cancer&amp;usg=ALkJrhjdd9LGT44SW9aqOFbsDIn8n97uWQ\">\u03bc\u03b9\u03ba\u03c1\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1<\/a>.<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>SURVIVIN<\/li>\n<\/ul>\n<p>\u0397 survivin \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03bc\u03bf\u03bd\u03b1\u03b4\u03b9\u03ba\u03cc\u03c2 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b5\u03ba\u03c6\u03c1\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b5\u03bc\u03b2\u03c1\u03c5\u03ca\u03ba\u03cc \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03cc\u03c1\u03b3\u03b1\u03bd\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5 \u03c3\u03c4\u03b1 \u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03be\u03b9\u03b1\u03ba\u03ac \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1, \u03b1\u03bb\u03bb\u03ac \u03bc\u03b7 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03c3\u03b9\u03bc\u03bf \u03c3\u03b5 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\u03c4\u03bf\u03c5 \u03b5\u03b3\u03ba\u03b5\u03c6\u03ac\u03bb\u03bf\u03c5, \u03bc\u03b5\u03bb\u03ac\u03bd\u03c9\u03bc\u03b1, \u03bd\u03b5\u03c5\u03c1\u03bf\u03b2\u03bb\u03ac\u03c3\u03c4\u03c9\u03bc\u03b1, \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b9\u03c2 \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03ba\u03bf\u03ae\u03b8\u03b5\u03b9\u03b5\u03c2, \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03ac\u03bb\u03bb\u03c9\u03bd. \u039c\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c3\u03b5 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03af\u03c9\u03c3\u03b1\u03bd \u03c4\u03b7\u03bd \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 survivin \u03c3\u03b5 \u03cc\u03b3\u03ba\u03bf\u03c5\u03c2 \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03c4\u03c9\u03bd \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03b9\u03c3\u03c4\u03ce\u03bd. \u0395\u03c0\u03b9\u03c0\u03c1\u03bf\u03c3\u03b8\u03ad\u03c4\u03c9\u03c2, \u03b7 \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 (up-regulation) \u03c4\u03b7\u03c2 \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 survivin \u03c3\u03c4\u03b1 \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03b7 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc \u03ba\u03cd\u03ba\u03bb\u03bf, \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03bc\u03b9\u03b1 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b9\u03b1\u03c0\u03bf\u03c0\u03c4\u03c9\u03c4\u03b9\u03ba\u03bf\u03cd 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H \u03b4\u03c5\u03bd\u03b1\u03bc\u03b9\u03ba\u03ae \u03b5\u03bd\u03b4\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 \u03c4\u03bf\u03c5 survivin \u03c3\u03b5 \u03cc\u03b3\u03ba\u03bf\u03c5\u03c2 (\u03b4\u03b7\u03bb\u03b1\u03b4\u03ae, \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03bf\u03c0\u03bb\u03b1\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c0\u03c5\u03c1\u03b7\u03bd\u03b9\u03ba\u03ce\u03bd) \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03b5\u03cd\u03c3\u03b5\u03b9 \u03c9\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03bf\u03c5 survivin \u03ba\u03b1\u03b9 \u03c9\u03c2 \u03c0\u03c1\u03bf\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03c3\u03b5 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\u03ba\u03b1\u03b9 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03b2\u03af\u03c9\u03c3\u03b7 \u03c3\u03b5 \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03b5\u03c2 \u03ba\u03b1\u03ba\u03bf\u03ae\u03b8\u03b5\u03b9\u03b5\u03c2, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03bc\u03b7-\u03bc\u03b9\u03ba\u03c1\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03bf\u03cd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1, \u03c4\u03bf\u03c5 \u03c3\u03c4\u03bf\u03bc\u03ac\u03c7\u03bf\u03c5, \u03c4\u03bf\u03c5 \u03c0\u03b1\u03c7\u03ad\u03bf\u03c2 \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5, \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd, \u03c4\u03bf\u03c5 \u03bd\u03b5\u03c5\u03c1\u03bf\u03b2\u03bb\u03b1\u03c3\u03c4\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, \u03ba\u03b1\u03b9 \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03ba\u03bf\u03b7\u03b8\u03b5\u03b9\u03ce\u03bd. \u0391\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 survivin \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03c3\u03c4\u03b7\u03ba\u03b5 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae\u03c2, \u03c4\u03bf\u03c0\u03b9\u03ba\u03ae \u03b5\u03b9\u03c3\u03b2\u03bf\u03bb\u03ae \u03c3\u03c4\u03bf\u03c5\u03c2  \u03bb\u03b5\u03bc\u03c6\u03b1\u03b4\u03ad\u03bd\u03b5\u03c2, \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7. \u03a4\u03ad\u03bb\u03bf\u03c2, \u03c5\u03c0\u03b5\u03c1\u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 survivin \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03c0\u03c1\u03bf\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc \u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c3\u03b5 \u03c7\u03b7\u03bc\u03b5\u03b9\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03ba\u03c4\u03b9\u03bd\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03b7\u03c2 \u03bf\u03c5\u03c1\u03bf\u03b4\u03cc\u03c7\u03bf\u03c5 \u03ba\u03cd\u03c3\u03c4\u03b7\u03c2, \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd, \u03c3\u03c4\u03bf \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03cc \u03bc\u03c5\u03ad\u03bb\u03c9\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03bb\u03ad\u03bc\u03c6\u03c9\u03bc\u03b1. \u0395\u03af\u03bd\u03b1\u03b9 \u03c3\u03b1\u03c6\u03ad\u03c2 \u03cc\u03c4\u03b9 \u03bf \u03c1\u03cc\u03bb\u03bf\u03c2 \u03c4\u03bf\u03c5 survivin \u03c3\u03c4\u03b7 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c5\u03c0\u03b5\u03c1\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c0\u03bf\u03bb\u03cd \u03c4\u03b7\u03bd \u03b1\u03c0\u03bb\u03ae \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7\u03c2. \u0395\u03ba\u03c4\u03cc\u03c2 \u03b1\u03c0\u03cc \u03c4o\u03bd \u03ac\u03bc\u03b5\u03c3\u03bf \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03bf\u03b3\u03ad\u03bd\u03b5\u03c3\u03b7, \u03c4\u03bf survivin \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03b4\u03c1\u03b1\u03bc\u03b1\u03c4\u03af\u03c3\u03b5\u03b9 \u03ad\u03bd\u03b1\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7\u03bd \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03b3\u03ad\u03bd\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5, \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03b5\u03ba\u03c6\u03c1\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03c3\u03c4\u03b1 \u03b5\u03bd\u03b4\u03bf\u03b8\u03b7\u03bb\u03b9\u03b1\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03b3\u03ad\u03bd\u03b5\u03c3\u03b7\u03c2. \u03a0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf survivin \u03c0\u03b1\u03af\u03b6\u03b5\u03b9 \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7\u03bd \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c7\u03b7\u03bc\u03b5\u03b9\u03bf\u03b1\u03bd\u03b8\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1. \u0388\u03c7\u03b5\u03b9 \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03c7\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03b1\u03bd\u03b1\u03c3\u03c4\u03ad\u03bb\u03bb\u03b5\u03b9 \u03c4\u03bf\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc \u03b8\u03ac\u03bd\u03b1\u03c4\u03bf \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03bf\u03c5\u03c2 \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03c4\u03c9\u03bd paclitaxel, etoposide \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 \u03bd\u03ad\u03ba\u03c1\u03c9\u03c3\u03b7\u03c2 \u03cc\u03b3\u03ba\u03c9\u03bd-\u03b1 \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03bf\u03b9 \u03b9\u03bd\u03bf\u03b2\u03bb\u03ac\u03c3\u03c4\u03b5\u03c2 \u039d\u0399\u0397 3\u03a43 \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03bf\u03b9 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c5\u03c0\u03bf\u03c3\u03c4\u03b5\u03af \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 \u03c0\u03b1\u03ba\u03bb\u03b9\u03c4\u03b1\u03be\u03ad\u03bb\u03b7 (paclitaxel) \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7 \u03cc\u03c4\u03b1\u03bd \u03b5\u03ba\u03c6\u03c1\u03ac\u03b6\u03bf\u03c5\u03bd \u03b1\u03bd\u03b1\u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03ad\u03bd\u03bf survivin. \u039c\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 in vitro \u03ba\u03b1\u03b9 in vivo \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03cc\u03c4\u03b9 \u03b7 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 survivin \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03bf \u03b4\u03c5\u03bd\u03b1\u03bc\u03b9\u03ba\u03cc \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c4\u03bf\u03c0\u03bf\u03b9\u03b5\u03af \u03c4\u03b1 \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c3\u03b5 \u03c7\u03b7\u03bc\u03b5\u03b9\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2, \u03cc\u03c0\u03c9\u03c2 paclitaxel, cisplatin, etoposide, \u03b1\u03ba\u03c4\u03b9\u03bd\u03bf\u03b2\u03bf\u03bb\u03af\u03b1 \u03b3\u03ac\u03bc\u03bc\u03b1, \u03ba\u03b1\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1.<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>&nbsp; BCL2 Bcl-2 ( B-cell lymphoma 2 ) is the founding member of the\u00a0Bcl-2 family\u00a0of\u00a0apoptosis\u00a0regulator proteins\u00a0encoded by the BCL2\u00a0gene. The Bcl-2 gene has been implicated in a number of\u00a0cancers, including\u00a0melanoma,\u00a0breast,\u00a0prostate,\u00a0chronic lymphocytic leukemia, and\u00a0lung carcinomas, as well as\u00a0schizophrenia\u00a0and\u00a0autoimmunity. It is also thought to be involved in resistance to conventional cancer treatment. This suggests that decreased apoptosis<\/p>","protected":false},"author":1,"featured_media":0,"parent":3117,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-3179","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/pages\/3179","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/comments?post=3179"}],"version-history":[{"count":3,"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/pages\/3179\/revisions"}],"predecessor-version":[{"id":4435,"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/pages\/3179\/revisions\/4435"}],"up":[{"embeddable":true,"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/pages\/3117"}],"wp:attachment":[{"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/media?parent=3179"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}