{"id":3186,"date":"2021-07-09T11:53:49","date_gmt":"2021-07-09T11:53:49","guid":{"rendered":"https:\/\/www.molecular-view.com\/?page_id=3186"},"modified":"2021-08-25T11:51:24","modified_gmt":"2021-08-25T11:51:24","slug":"gene_expression_of_tumor_suppressor_genes","status":"publish","type":"page","link":"https:\/\/www.molecular-view.com\/el\/services\/cancer\/prognosis_diagnosis\/gene_expression_of_tumor_suppressor_genes\/","title":{"rendered":"\u0393\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ae \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 (\u03c0\u03bf\u03c3\u03bf\u03c4\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7) \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03c9\u03bd \u03cc\u03b3\u03ba\u03c9\u03bd"},"content":{"rendered":"<div id=\"pl-3186\"  class=\"panel-layout\" ><div id=\"pg-3186-0\"  class=\"panel-grid panel-has-style\" ><div class=\"divider-no-animation panel-row-style panel-row-style-for-3186-0\" ><div id=\"pgc-3186-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-3186-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\" ><div class=\"orion custom default panel-widget-style panel-widget-style-for-3186-0-0-0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t><h3 class=\"widget-title\">\u0393\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ae \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 (\u03c0\u03bf\u03c3\u03bf\u03c4\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7) \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03c9\u03bd \u03cc\u03b3\u03ba\u03c9\u03bd<\/h3>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>&nbsp;<\/p>\n<ul>\n<li>P53 (\u03cc\u03b3\u03ba\u03bf\u03b9 \u03c4\u03bf\u03c5 \u03b5\u03b3\u03ba\u03b5\u03c6\u03ac\u03bb\u03bf\u03c5, \u03c3\u03b1\u03c1\u03ba\u03ce\u03bc\u03b1\u03c4\u03b1, \u03bb\u03b5\u03c5\u03c7\u03b1\u03b9\u03bc\u03af\u03b1, \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd)<\/li>\n<\/ul>\n<p>\u0397 p53 (\u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae \u03c9\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u03af\u03bd\u03b7 53 \u03ae \u03cc\u03b3\u03ba\u03bf\u03c5 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 53), \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dp53%2Bwikipedia%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Tumor_suppressor&amp;usg=ALkJrhir5_wAL6ewcpaY-BK7LrhuIX-EFg\">\u03bf\u03b3\u03ba\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7<\/a>\u00a0\u03c0\u03bf\u03c5 \u03c3\u03c4\u03bf\u03bd \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf \u03ba\u03c9\u03b4\u03b9\u03ba\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03a4\u03a153. \u0397 p53 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b7 \u03c3\u03b5\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dp53%2Bwikipedia%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Multicellular_organism&amp;usg=ALkJrhhZmUC159kAtTkSwaPzCl0Uo9lUXg\">\u03c0\u03bf\u03bb\u03c5\u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03bf\u03c5\u03c2 \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2<\/a>\u00a0, \u03cc\u03c0\u03bf\u03c5 \u03c1\u03c5\u03b8\u03bc\u03af\u03b6\u03b5\u03b9 \u03c4\u03bf\u03bd\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dp53%2Bwikipedia%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Cell_cycle&amp;usg=ALkJrhgbhaWrVx7RrogXyG-ReV95DQabMg\">\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc \u03ba\u03cd\u03ba\u03bb\u03bf<\/a>\u00a0\u03ba\u03b1\u03b9 \u03ad\u03c4\u03c3\u03b9 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03c9\u03c2\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dp53%2Bwikipedia%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Tumor_suppressor&amp;usg=ALkJrhir5_wAL6ewcpaY-BK7LrhuIX-EFg\">\u03bf\u03b3\u03ba\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7<\/a>\u00a0\u03c0\u03bf\u03c5 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03c4\u03bf\u03c5\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dp53%2Bwikipedia%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Cancer&amp;usg=ALkJrhjqN002U-c6NXKrsEJdObAvi5I8HA\">\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5<\/a>. \u0397 P53 \u03ad\u03c7\u03b5\u03b9 \u03c0\u03bf\u03bb\u03bb\u03bf\u03cd\u03c2 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03bc\u03b5 \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b5\u03c2, \u03ba\u03b1\u03b9 \u03c0\u03b1\u03af\u03b6\u03b5\u03b9 \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7\u03bd \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7, \u03c4\u03b7 \u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1, \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dp53%2Bwikipedia%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Angiogenesis&amp;usg=ALkJrhiQrQf7T24DmQD39GbipThLLvmuSw\">\u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03b3\u03ad\u03bd\u03b5\u03c3\u03b7\u03c2<\/a>\u00a0\u0395\u03ac\u03bd \u03c4\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03a153 \u03ad\u03c7\u03b5\u03b9 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b5\u03af \u03b2\u03bb\u03ac\u03b2\u03b7, \u03c4\u03cc\u03c4\u03b5 \u03b7 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ac.<\/p>\n<ul>\n<li>NF1 (neurofibromas, sarcomas, gliomas)<\/li>\n<li>NF2 (Schwann cell tumors, astrocytomas, meningiomas, ependymonas)<\/li>\n<li>STAT3 (many cancers)<\/li>\n<li>P16INK4a (many cancers)<\/li>\n<\/ul>\n<ul>\n<li>BRCA1 (\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03c9\u03bf\u03b8\u03b7\u03ba\u03ce\u03bd)<\/li>\n<\/ul>\n<p>To BRCA1 (<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Breast_cancer&amp;usg=ALkJrhht9B3D2ww6s13sD-_HidzRZOt-vA\">\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd<\/a>\u00a0), \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03bf\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Caretaker_gene&amp;usg=ALkJrhg0qAhUZFfWUcnkjJbz8p0bgFy1gg\">\u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf-\u03b5\u03c0\u03b9\u03c3\u03c4\u03ac\u03c4\u03b7\u03c2<\/a>\u00a0\u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03c0\u03b1\u03c1\u03ac\u03b3\u03b5\u03b9 \u03bc\u03b9\u03b1\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Protein&amp;usg=ALkJrhgY_1NycHHHGU3V-YEPYOnisz3GbA\">\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7<\/a>\u00a0\u03c0\u03bf\u03c5 \u03bf\u03bd\u03bf\u03bc\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd \u03c4\u03cd\u03c0\u03bf\u03c5 1 \u03ba\u03b1\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03b5\u03cd\u03b8\u03c5\u03bd\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03b4\u03b9\u03cc\u03c1\u03b8\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 DNA.  \u039f\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c4\u03bf\u03c5 BRCA1 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 \u03bf\u03b4\u03b7\u03b3\u03bf\u03cd\u03bd \u03c3\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b3\u03b9\u03b1\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Breast_cancer&amp;usg=ALkJrhht9B3D2ww6s13sD-_HidzRZOt-vA\">\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd<\/a>\u00a0\u03c9\u03c2 \u03bc\u03ad\u03c1\u03bf\u03c5\u03c2 \u03b5\u03bd\u03cc\u03c2\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Hereditary_breast-ovarian_cancer_syndrome&amp;usg=ALkJrhiiTHOcDXNknBHoE45k2MVaEi9qCg\">\u03ba\u03bb\u03b7\u03c1\u03bf\u03bd\u03bf\u03bc\u03b9\u03ba\u03bf\u03cd, \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd-\u03c9\u03bf\u03b8\u03b7\u03ba\u03ce\u03bd, \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5<\/a>\u0388\u03c7\u03bf\u03c5\u03bd \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03b8\u03b5\u03af \u03b5\u03ba\u03b1\u03c4\u03bf\u03bd\u03c4\u03ac\u03b4\u03b5\u03c2\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Mutation&amp;usg=ALkJrhhbXT3zFNI8EOEVpyiGy3lbTWptCg\">\u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2<\/a>\u00a0\u03c3\u03c4\u03bf BRCA1 \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf, \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5. \u0393\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc BRCA1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03ad\u03c7\u03c1\u03b9 \u03ba\u03b1\u03b9 60% \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03c0\u03c4\u03cd\u03be\u03bf\u03c5\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03c9\u03bd 90 \u03b5\u03c4\u03ce\u03bd, \u03b5\u03bd\u03ce 55% \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c3\u03c4\u03b9\u03c2 \u03c9\u03bf\u03b8\u03ae\u03ba\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03bf\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf BRCA1 \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf. \u0395\u03ba\u03c4\u03cc\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd, \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf BRCA1 \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b1\u03c5\u03be\u03ac\u03bd\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b3\u03b9\u03b1\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Ovarian_cancer&amp;usg=ALkJrhjE9_Tq0-VCe7BwF7grLb2Qk65QMA\">\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03c9\u03bd \u03c9\u03bf\u03b8\u03b7\u03ba\u03ce\u03bd<\/a>,\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Fallopian_tube&amp;usg=ALkJrhgjeCxravt3HtkTCTcvvMIvj-OxiA\">\u03c4\u03b7\u03c2 \u03c3\u03ac\u03bb\u03c0\u03b9\u03b3\u03b3\u03b1\u03c2<\/a>\u03ba\u03b1\u03b9\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Prostate_cancer&amp;usg=ALkJrhgXxlpMxG1gsruc30C2xN6bWMv6CA\">\u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c4\u03ac\u03c4\u03b7<\/a>\u039c\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf BRCA1 \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03bf \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ac \u03c3\u03c5\u03bd\u03b7\u03b8\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c2, \u03ce\u03c3\u03c4\u03b5 \u03bf\u03b9 \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b1  \u03bd\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03bc\u03cc\u03bd\u03bf \u03ad\u03c9\u03c2 \u03c4\u03bf 10 \u03c4\u03bf\u03b9\u03c2 \u03b5\u03ba\u03b1\u03c4\u03cc \u03cc\u03bb\u03c9\u03bd \u03c4\u03c9\u03bd \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03c9\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd \u03c3\u03c4\u03b9\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2. \u039c\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf BRCA1 \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c5\u03be\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03c9\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03c9\u03bd \u03cc\u03c0\u03c9\u03c2\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Colon_cancer&amp;usg=ALkJrhgKpvfD2Wn1n2JTzon9oPV65Vx4MA\">\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c0\u03b1\u03c7\u03ad\u03bf\u03c2 \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5<\/a>,\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Pancreatic_cancer&amp;usg=ALkJrhgVWhQreQ2UGroKgaUQfrbBmXMzGQ\">\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c0\u03b1\u03b3\u03ba\u03c1\u03ad\u03b1\u03c4\u03bf\u03c2<\/a>\u03ba\u03b1\u03b9\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dbrca1%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvns&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Prostate_cancer&amp;usg=ALkJrhgXxlpMxG1gsruc30C2xN6bWMv6CA\">\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c4\u03ac\u03c4\u03b7<\/a>. \u03a4\u03bf BRCA1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03c0\u03bf\u03bb\u03c5\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b5\u03bc\u03c0\u03bb\u03b1\u03ba\u03b5\u03af \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ad\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b5\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03b5\u03c0\u03b9\u03b4\u03b9\u03cc\u03c1\u03b8\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 DNA, \u03b7 \u03bc\u03b5\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03b9\u03ba\u03ae \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7, \u03c4\u03bf \u03c3\u03b7\u03bc\u03b5\u03af\u03bf \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03bf\u03cd \u03ba\u03cd\u03ba\u03bb\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b7 \u03bf\u03c5\u03b2\u03b9\u03ba\u03b9\u03c4\u03b9\u03bd\u03af\u03c9\u03c3\u03b7. \u039a\u03b1\u03c4\u03ac \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b1, \u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03ae \u03b7 \u03b1\u03c0\u03bf\u03c5\u03c3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae\u03c2 \u0392RC\u03911 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c7\u03b7\u03bc\u03b5\u03b9\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1. \u0391\u03c1\u03c7\u03b9\u03ba\u03ac \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03c5\u03c0\u03b5\u03c1\u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 BRCA1 \u03c3\u03b5 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03b5\u03c2 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ad\u03c2 \u03c3\u03b5\u03b9\u03c1\u03ad\u03c2 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd \u03ba\u03b1\u03c4\u03b1\u03bb\u03ae\u03b3\u03b5\u03b9 \u03c3\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03c3\u03b9\u03c3\u03c0\u03bb\u03b1\u03c4\u03af\u03bd\u03b7. \u03a0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9, \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 \u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03bf\u03cd\u03c2 \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 BRCA1 \u03c0\u03c1\u03bf\u03c9\u03b8\u03b5\u03af \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u03c3\u03b9\u03c3\u03c0\u03bb\u03b1\u03c4\u03af\u03bd\u03b7 (cisplatin) \u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03b9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c0\u03b9\u03b4\u03b9\u03cc\u03c1\u03b8\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 DNA \u03b1\u03c0\u03cc NER \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7.<\/p>\n<ul>\n<li>BRCA2 (\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03c9\u03bf\u03b8\u03b7\u03ba\u03ce\u03bd)<\/li>\n<\/ul>\n<p>\u03a4\u03bf BRCA2 \u03cc\u03c0\u03c9\u03c2 \u03c4\u03bf BRCA1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03c0\u03bf\u03c5 \u03b1\u03bd\u03ae\u03ba\u03b5\u03b9 \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03af\u03b1 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae \u03c9\u03c2 \u03bf\u03b3\u03ba\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ac. \u03a3\u03b5 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac\u00a0<a href=\"http:\/\/www.cancer.gov\/Common\/PopUps\/popDefinition.aspx?id=CDR0000046476&amp;version=Patient&amp;language=English\">\u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1<\/a>\u03c4\u03b1 BRCA1 \u03ba\u03b1\u03b9 BRCA2 \u03b2\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03b9\u03c3\u03c4\u03b5\u03af \u03b7 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c5\u03bb\u03b9\u03ba\u03bf\u03cd \u03c4\u03bf\u03c5 \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03bf\u03c5 (<a href=\"http:\/\/www.cancer.gov\/Common\/PopUps\/popDefinition.aspx?id=CDR0000045671&amp;version=Patient&amp;language=English\">DNA<\/a>) \u03ba\u03b1\u03b9 \u03b2\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03b5\u03be\u03ad\u03bb\u03b5\u03b3\u03ba\u03c4\u03b7 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7. \u039c\u03b5\u03c4\u03ac\u03bb\u03bb\u03b1\u03be\u03b7 \u03b1\u03c5\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c5\u03bd\u03b4\u03b5\u03b8\u03b5\u03af \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bb\u03b7\u03c1\u03bf\u03bd\u03bf\u03bc\u03b9\u03ba\u03bf\u03cd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03c9\u03bf\u03b8\u03b7\u03ba\u03ce\u03bd. \u0394\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03bb\u03b5\u03c2 \u03bf\u03b9 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5, \u03ae \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03b5\u03c0\u03b9\u03b2\u03bb\u03b1\u03b2\u03ae\u03c2. \u039c\u03b5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c5\u03b5\u03c1\u03b3\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2, \u03b5\u03bd\u03ce \u03ac\u03bb\u03bb\u03b5\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b7\u03bd \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03ae \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 (\u03bf\u03c5\u03b4\u03ad\u03c4\u03b5\u03c1\u03b7). \u0395\u03c0\u03b9\u03b2\u03bb\u03b1\u03b2\u03b5\u03af\u03c2 \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c5\u03be\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03bd\u03cc\u03c2 \u03b1\u03c4\u03cc\u03bc\u03bf\u03c5 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03c0\u03c4\u03cd\u03be\u03b5\u03b9 \u03bc\u03b9\u03b1 \u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2. \u039c\u03b9\u03b1\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b1\u03c2 \u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5  \u03c4\u03bf\u03c5 \u03c3\u03c4\u03ae\u03b8\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9\/ \u03ae \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03c9\u03bd \u03c9\u03bf\u03b8\u03b7\u03ba\u03ce\u03bd \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03b5\u03ac\u03bd \u03b1\u03c5\u03c4\u03ae \u03ba\u03bb\u03b7\u03c1\u03bf\u03bd\u03bf\u03bc\u03b5\u03af \u03ad\u03bd\u03b1 \u03b4\u03b7\u03bb\u03b7\u03c4\u03b7\u03c1\u03b9\u03ce\u03b4\u03b5\u03c2 (\u03b5\u03c0\u03b9\u03b2\u03bb\u03b1\u03b2\u03ad\u03c2) BRCA1 \u03ae BRCA2. \u0386\u03bd\u03b4\u03c1\u03b5\u03c2 \u03bc\u03b5 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd. \u03a4\u03cc\u03c3\u03bf \u03bf\u03b9 \u03ac\u03bd\u03b4\u03c1\u03b5\u03c2 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03c0\u03b9\u03b2\u03bb\u03b1\u03b2\u03b5\u03af\u03c2 BRCA1 \u03ae BRCA2 \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c4\u03c1\u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03c9\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03c9\u03bd. \u0391\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03b5\u03c0\u03b9\u03b2\u03bb\u03b1\u03b2\u03ae BRCA1 \u03ae BRCA2 \u03bc\u03b5\u03c4\u03ac\u03bb\u03bb\u03b1\u03be\u03b7, \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ad\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03bf\u03c5\u03bd \u03ad\u03bd\u03b1 \u03c0\u03c1\u03cc\u03c3\u03c9\u03c0\u03bf \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c7\u03b5\u03b9\u03c1\u03b9\u03c3\u03c4\u03b5\u03af \u03c4\u03bf\u03c5 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5. \u03a3\u03b5 \u03bc\u03b9\u03b1 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03bc\u03b5 \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd \u03ba\u03b1\u03b9\/\u03ae \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03c9\u03bd \u03c9\u03bf\u03b8\u03b7\u03ba\u03ce\u03bd, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03ba\u03b1\u03c4\u03b1\u03c4\u03bf\u03c0\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b4\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03c4\u03b5\u03af \u03c0\u03c1\u03ce\u03c4\u03b1 \u03ad\u03bd\u03b1 \u03bc\u03ad\u03bb\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c3\u03c4\u03ae\u03b8\u03bf\u03c5\u03c2 \u03ae \u03c4\u03c9\u03bd \u03c9\u03bf\u03b8\u03b7\u03ba\u03ce\u03bd. \u0391\u03bd \u03c4\u03bf \u03c0\u03c1\u03cc\u03c3\u03c9\u03c0\u03bf \u03b1\u03c5\u03c4\u03cc \u03ad\u03c7\u03b5\u03b9 \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b5\u03c0\u03b9\u03b2\u03bb\u03b1\u03b2\u03ae \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03b1 BRCA1 \u03ae BRCA2, \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03ac\u03bb\u03bb\u03b1 \u03bc\u03ad\u03bb\u03b7 \u03c4\u03b7\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03bb\u03b5\u03b3\u03c7\u03b8\u03bf\u03cd\u03bd \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03c9\u03b8\u03b5\u03af \u03b5\u03ac\u03bd \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c4\u03b7 \u03bc\u03b5\u03c4\u03ac\u03bb\u03bb\u03b1\u03be\u03b7.<\/p>\n<ul>\n<li>PTEN  (\u03b3\u03bb\u03bf\u03b9\u03ce\u03bc\u03b1\u03c4\u03b1, \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd, \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b8\u03c5\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2,\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03c9\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03bf\u03cd \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03c0\u03bb\u03b1\u03ba\u03ce\u03b4\u03bf\u03c5\u03c2 \u03c4\u03bf\u03c5 \u03bb\u03b1\u03b9\u03bc\u03bf\u03cd)<\/li>\n<\/ul>\n<p>PTEN \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dpten%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvnsz&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Protein&amp;usg=ALkJrhgwyXp8XWpkc44S7aAXrfO9DyPtLw\">\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7<\/a>\u00a0\u03c0\u03bf\u03c5 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03bf\u03c5\u03c2 \u03ba\u03c9\u03b4\u03b9\u03ba\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf PTEN\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dpten%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvnsz&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Gene&amp;usg=ALkJrhjHAMxSf1ftwZ0--Rq50tlVYVBQ0g\">\u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf<\/a>\u00a0. \u039c\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03b1\u03c5\u03c4\u03bf\u03cd \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03ad\u03bd\u03b1 \u03b2\u03ae\u03bc\u03b1 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c0\u03bf\u03bb\u03bb\u03ce\u03bd \u03bc\u03bf\u03c1\u03c6\u03ce\u03bd\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dpten%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvnsz&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Cancer&amp;usg=ALkJrhihCqFI_mLllyJCwaEo-lw4Qbit6g\">\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03c9\u03bd<\/a>\u00a0. \u03a4\u03bf PTEN \u03b4\u03c1\u03b1 \u03c9\u03c2\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dpten%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvnsz&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Tumor_suppressor_gene&amp;usg=ALkJrhghgnaJ31bQrHgMBHgRLTay9PmqiQ\">\u03bf\u03b3\u03ba\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03cc \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf<\/a>. \u038c\u03c4\u03b1\u03bd \u03c4\u03bf \u03ad\u03bd\u03b6\u03c5\u03bc\u03bf \u03c4\u03bf\u03c5 PTEN \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03c3\u03c9\u03c3\u03c4\u03ac, \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03c9\u03c2 \u03bc\u03ad\u03c1\u03bf\u03c2 \u03b5\u03bd\u03cc\u03c2 \u03c7\u03b7\u03bc\u03b9\u03ba\u03bf\u03cd \u03bc\u03bf\u03bd\u03bf\u03c0\u03b1\u03c4\u03b9\u03bf\u03cd \u03c0\u03bf\u03c5 \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c4\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c3\u03c4\u03bf \u03bd\u03b1 \u03c3\u03c4\u03b1\u03bc\u03b1\u03c4\u03ae\u03c3\u03bf\u03c5\u03bd \u03bd\u03b1 \u03b4\u03b9\u03b1\u03b9\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03bd\u03b1\u03b3\u03ba\u03ac\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03c5\u03c0\u03bf\u03b2\u03bb\u03b7\u03b8\u03bf\u03cd\u03bd \u03c3\u03b5 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc \u03b8\u03ac\u03bd\u03b1\u03c4\u03bf (\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dpten%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvnsz&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Apoptosis&amp;usg=ALkJrhiqFDxaHkZgjYEQqV6-sFYgdCGklA\">\u03b1\u03c0\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7<\/a>\u00a0) \u03cc\u03c4\u03b1\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf. \u0391\u03c5\u03c4\u03ad\u03c2 \u03bf\u03b9 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b5\u03c2 \u03c0\u03c1\u03bf\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b1\u03bd\u03b5\u03be\u03ad\u03bb\u03b5\u03b3\u03ba\u03c4\u03b7 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c4\u03bf \u03c3\u03c7\u03b7\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03cc \u03cc\u03b3\u03ba\u03c9\u03bd. \u03a5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b1\u03c0\u03bf\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03cc\u03c4\u03b9 \u03b7 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03a1\u03a4\u0395\u039d \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b1\u03af\u03b6\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03ba\u03af\u03bd\u03b7\u03c3\u03b7 (\u03bc\u03b5\u03c4\u03b1\u03bd\u03ac\u03c3\u03c4\u03b5\u03c5\u03c3\u03b7) \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03ba\u03cc\u03bb\u03bb\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03c3\u03b5 \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03b5\u03c2 \u03b9\u03c3\u03c4\u03bf\u03cd\u03c2. \u03a4\u03bf \u03a1\u03a4\u0395\u039d \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03c0\u03b9\u03bf \u03ba\u03bf\u03b9\u03bd\u03bf\u03cd\u03c2\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dpten%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvnsz&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Tumor_suppressor_gene&amp;usg=ALkJrhghgnaJ31bQrHgMBHgRLTay9PmqiQ\">\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 \u03cc\u03b3\u03ba\u03c9\u03bd<\/a>\u00a0\u03c0\u03bf\u03c5 \u03c7\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03bf \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf.  \u039a\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5 \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03c4\u03bf\u03c5 \u03a1\u03a4\u0395\u039d \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bc\u03b2\u03bf\u03cd\u03bd \u03c0\u03bf\u03c5 \u03b1\u03c0\u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd \u03c4\u03b7\u03bd \u03b5\u03bd\u03b6\u03c5\u03bc\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bf\u03b4\u03b7\u03b3\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf \u03c3\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03b1\u03c3\u03b9\u03b1\u03c3\u03bc\u03cc \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc \u03b8\u03ac\u03bd\u03b1\u03c4\u03bf. \u0397 \u03c3\u03c5\u03c7\u03bd\u03ae \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b4\u03c1\u03b1\u03bd\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03a1\u03a4\u0395\u039d \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dpten%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvnsz&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Glioblastoma&amp;usg=ALkJrhi0BcWqpWB4jmVLV3M5o5wfNugEEA\">\u03b3\u03bb\u03bf\u03b9\u03bf\u03b2\u03bb\u03ac\u03c3\u03c4\u03c9\u03bc\u03b1<\/a>,\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dpten%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvnsz&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Endometrial_cancer&amp;usg=ALkJrhhzv-l9v5PScGhK1KLeKxBwtyAOtQ\">\u03c3\u03c4\u03bf\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03b5\u03bd\u03b4\u03bf\u03bc\u03b7\u03c4\u03c1\u03af\u03bf\u03c5<\/a>\u03ba\u03b1\u03b9\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dpten%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvnsz&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Prostate_cancer&amp;usg=ALkJrhg2npfmlsJGUt7VAiBrfG_6KzDzSA\">\u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c4\u03ac\u03c4\u03b7<\/a>\u03b5\u03bd\u03ce \u03b5\u03bb\u03b1\u03c4\u03c4\u03c9\u03bc\u03ad\u03bd\u03b7 \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c5\u03bd\u03b1\u03bd\u03c4\u03ac\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ac \u03ac\u03bb\u03bb\u03b1 \u03b5\u03af\u03b4\u03b7 \u03cc\u03b3\u03ba\u03c9\u03bd \u03cc\u03c0\u03c9\u03c2 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd. \u0388\u03c9\u03c2 \u03ba\u03b1\u03b9 70% \u03c4\u03c9\u03bd \u03b1\u03bd\u03b4\u03c1\u03ce\u03bd \u03bc\u03b5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c4\u03ac\u03c4\u03b7 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c7\u03ac\u03c3\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03b1\u03bd\u03c4\u03af\u03b3\u03c1\u03b1\u03c6\u03bf \u03c4\u03bf\u03c5 \u03a1\u03a4\u0395\u039d \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2. \u03a1\u03a4\u0395\u039d \u03bc\u03b5\u03c4\u03ac\u03bb\u03bb\u03b1\u03be\u03b7 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bc\u03b9\u03b1 \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03af\u03b1 \u03ba\u03bb\u03b7\u03c1\u03bf\u03bd\u03bf\u03bc\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03bf\u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b5\u03c9\u03bd \u03b3\u03b9\u03b1 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf. \u039c\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03a1\u03a4\u0395\u039d \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03bf\u03c5\u03bd \u03bc\u03b9\u03b1 \u03c3\u03b5\u03b9\u03c1\u03ac \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ce\u03bd \u03cc\u03c0\u03c9\u03c2 \u03c4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf Cowden, \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03bc\u03b7 \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03cc\u03b3\u03ba\u03c9\u03bd \u03ba\u03b1\u03b9 \u03bf\u03bd\u03bf\u03bc\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9\u00a0<a href=\"http:\/\/translate.googleusercontent.com\/translate_c?hl=el&amp;prev=\/search%3Fq%3Dpten%26hl%3Del%26rlz%3D1W1NNVC_enGR491%26biw%3D1440%26bih%3D625%26prmd%3Dimvnsz&amp;rurl=translate.google.gr&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Hamartoma&amp;usg=ALkJrhhHtFk-Kxk95VrQgVJAAzyTpYGnnA\">\u03b1\u03bc\u03b1\u03c1\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1<\/a>\u00a0.<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>CDH1 (gastric cancer, lobular breast cancer)<\/li>\n<li>MEN1 (parathyroid and pituitary adenomas, islet cell tumors, carcinoid)<\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>&nbsp; P53 p53 (also known as protein 53 or tumor protein 53), is a\u00a0tumor suppressor\u00a0protein that in humans is encoded by the TP53 gene. p53 is crucial in\u00a0multicellular organisms\u00a0, where it regulates the\u00a0cell cycle\u00a0and, thus, functions as a\u00a0tumor suppressor\u00a0that is involved in preventing\u00a0cancer. p53 has many mechanisms of anticancer function, and plays a role in<\/p>","protected":false},"author":1,"featured_media":0,"parent":3117,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-3186","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/pages\/3186","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/comments?post=3186"}],"version-history":[{"count":2,"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/pages\/3186\/revisions"}],"predecessor-version":[{"id":4436,"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/pages\/3186\/revisions\/4436"}],"up":[{"embeddable":true,"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/pages\/3117"}],"wp:attachment":[{"href":"https:\/\/www.molecular-view.com\/el\/wp-json\/wp\/v2\/media?parent=3186"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}